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1

Self-Assembled pH-Sensitive Nanoparticles: A Platform for Oral Delivery of Protein Drugs

Kiran Sonaje, Kun-Ju Lin, Jiun-Jie Wang, Fwu-Long Mi, Chiung-Tong Chen, Jyuhn-Huarng Juang, Hsing-Wen Sung

Journal:

Advanced Functional Materials

Year:

2010

Language:

english

File:

PDF, 596 KB

english, 2010

2

In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery

Kiran Sonaje, Yu-Hsin Lin, Jyuhn-Huarng Juang, Shiaw-Pyng Wey, Chiung-Tong Chen, Hsing-Wen Sung

Journal:

Year:

2009

Language:

english

File:

PDF, 1.31 MB

english, 2009

3

Effects of pH on molecular mechanisms of chitosan–integrin interactions and resulting tight-junction disruptions

Li-Wen Hsu, Yi-Cheng Ho, Er-Yuan Chuang, Chiung-Tong Chen, Jyuhn-Huarng Juang, Fang-Yi Su, Shiaw-Min Hwang, Hsing-Wen Sung

Journal:

Year:

2013

Language:

english

File:

PDF, 3.15 MB

english, 2013

4

Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems

Lin, Yu-Jung, Mi, Fwu-Long, Lin, Po-Yen, Miao, Yang-Bao, Huang, Tringyo, Chen, Kuan-Hung, Chen, Chiung-Tong, Chang, Yen, Sung, Hsing-Wen

Journal:

Advanced Drug Delivery Reviews

Year:

2018

Language:

english

File:

PDF, 1.28 MB

english, 2018

5

Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)

Wen-Hsing Lin, Shu-Yi Hsieh, Shih-Chieh Yen, Chiung-Tong Chen, Teng-Kuang Yeh, Tsu Hsu, Cheng-Tai Lu, Ching-Ping Chen, Chun-Wha Chen, Ling-Hui Chou, Yu-Lin Huang, An-Huei Cheng, Yun-I Chang, Ya-Ju Tse

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 795 KB

english, 2011

6

Sex Differences in High-fat Diet-induced Obesity, Metabolic Alterations and Learning, and Synaptic Plasticity Deficits in Mice

Ling-Ling Hwang, Chien-Hua Wang, Tzu-Ling Li, Shih-Dar Chang, Li-Chun Lin, Ching-Ping Chen, Chiung-Tong Chen, Keng-Chen Liang, Ing-Kang Ho, Wei-Shiung Yang, Lih-Chu Chiou

Journal:

Year:

2010

Language:

english

File:

PDF, 236 KB

english, 2010

7

Preparation of Nanoparticles Composed of Chitosan/Poly-γ-glutamic Acid and Evaluation of Their Permeability through Caco-2 Cells

Lin, Yu-Hsin, Chung, Ching-Kuang, Chen, Chiung-Tong, Liang, Hsiang-Fa, Chen, Sung-Ching, Sung, Hsing-Wen

Journal:

Biomacromolecules

Year:

2005

Language:

english

File:

PDF, 275 KB

english, 2005

8

Discovery of Novel N -β- d -Xylosylindole Derivatives as Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes

Yao, Chun-Hsu, Song, Jen-Shin, Chen, Chiung-Tong, Yeh, Teng-Kuang, Hung, Ming-Shiu, Chang, Chih-Chun, Liu, Yu-Wei, Yuan, Mao-Chia, Hsieh, Chieh-Jui, Huang, Chung-Yu, Wang, Min-Hsien, Chiu, Ching-Hui,

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

9

Oral Delivery of Peptide Drugs Using Nanoparticles Self-Assembled by Poly(γ-glutamic acid) and a Chitosan Derivative Functionalized by Trimethylation

Mi, Fwu-Long, Wu, Yong-Yi, Lin, Yu-Hsin, Sonaje, Kiran, Ho, Yi-Cheng, Chen, Chiung-Tong, Juang, Jyuhn-Huarng, Sung, Hsing-Wen

Journal:

Bioconjugate Chemistry

Year:

2008

Language:

english

File:

PDF, 2.34 MB

english, 2008

10

Development of Stem Cell Mobilizing Agents Targeting CXCR4 Receptor for Peripheral Blood Stem Cell Transplantation and Beyond

Wu, Chien-Huang, Song, Jen-Shin, Kuan, Hsuan-Hao, Wu, Szu-Huei, Chou, Ming-Chen, Jan, Jiing-Jyh, Tsou, Lun Kelvin, Ke, Yi-Yu, Chen, Chiung-Tong, Yeh, Kai-Chia, Wang, Sing-Yi, Yeh, Teng-Kuang, Tseng, C

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.70 MB

english, 2018

11

A bubble bursting-mediated oral drug delivery system that enables concurrent delivery of lipophilic and hydrophilic chemotherapeutics for treating pancreatic tumors in rats

Chen, Kuan-Hung, Miao, Yang-Bao, Shang, Chun-Yu, Huang, Tring-Yo, Yu, Yu-Tzu, Yeh, Chun-Nan, Song, Hsiang-Lin, Chen, Chiung-Tong, Mi, Fwu-Long, Lin, Kun-Ju, Sung, Hsing-Wen

Journal:

Year:

2020

File:

PDF, 15.14 MB

2020

12

Inhibition of human vascular endothelial cells proliferation by terbinafine

Pei-Yin Ho, Yu-Chih Liang, Yuan-Soon Ho, Chiung-Tong Chen, Wen-Sen Lee

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 586 KB

english, 2004

13

Enhanced oral bioavailability of paclitaxel by d-α-tocopheryl polyethylene glycol 400 succinate in mice

Pei-Yin Ho, Teng-Kuang Yeh, Hsien-Tsung Yao, Heng-Liang Lin, Hsin-Yi Wu, Yu-Kang Lo, Yi-Wei Chang, Tien-Hui Chiang, Stephen H.W. Wu, Yu-Sheng Chao, Chiung-Tong Chen

Journal:

International Journal of Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 545 KB

english, 2008

14

Paclitaxel-loaded poly(γ-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer

Hsiang-Fa Liang, Chiung-Tong Chen, Sung-Ching Chen, Anandrao R. Kulkarni, Ya-Ling Chiu, Mei-Chin Chen, Hsing-Wen Sung

Journal:

Year:

2006

Language:

english

File:

PDF, 470 KB

english, 2006

15

Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors

Ting-Yueh Tsai, Tsu Hsu, Chiung-Tong Chen, Jai-Hong Cheng, Teng-Kuang Yeh, Xin Chen, Chung-Yu Huang, Chung-Nien Chang, Kai-Chia Yeh, Su-Huei Hsieh, Chia-Hui Chien, Yi-Wei Chang, Chih-Hsiang Huang, Yu-

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 556 KB

english, 2009

16

Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors

Ting-Yueh Tsai, Mohane Selvaraj Coumar, Tsu Hsu, Hsing-Pang Hsieh, Chia-Hui Chien, Chiung-Tong Chen, Chung-Nien Chang, Yu-Kang Lo, Ssu-Hui Wu, Chung-Yu Huang, Yu-Wen Huang, Min-Hsien Wang, Hsin-Yi Wu,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 145 KB

english, 2006

17

Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors

Ting-Yueh Tsai, Tsu Hsu, Chiung-Tong Chen, Jai-Hong Cheng, Mei-Chun Chiou, Chih-Hsiang Huang, Ya-Ju Tseng, Teng-Kuang Yeh, Chung-Yu Huang, Kai-Chia Yeh, Yu-Wen Huang, Ssu-Hui Wu, Min-Hsien Wang, Xin C

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.61 MB

english, 2009

18

Development and validation of a liquid chromatography–tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study

Yi-Wei Chang, Wei-Cheng Chen, Ke-Ta Lin, Ling Chang, Hsien-Tsung Yao, Hsing-Pang Hsieh, Shih-Jung Lan, Chiung-Tong Chen, Yu-Sheng Chao, Teng-Kuang Yeh

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 438 KB

english, 2007

19

A Natural Compound (Ginsenoside Re) Isolated fromPanax ginsengas a Novel Angiogenic Agent for Tissue Regeneration

Ya-Chun Huang, Chiung-Tong Chen, Sung-Ching Chen, Po-Hong Lai, Huang-Chien Liang, Yen Chang, Lin-Chien Yu, Hsing-Wen Sung

Journal:

Pharmaceutical Research

Year:

2005

Language:

english

File:

PDF, 829 KB

english, 2005

20

Human Breast Tumor Cells Express Multimodal Imaging Reporter Genes

Kurt M. Lin, Ching-Han Hsu, Wun-Shaing W. Chang, Chiung-Tong Chen, Te-Wei Lee, Chin-Tu Chen

Journal:

Molecular Imaging and Biology

Year:

2008

Language:

english

File:

PDF, 503 KB

english, 2008

21

Effects of paclitaxel and doxorubicin in histocultures of hepatocelular carcinomas

Jiunn-Jye Chuu, Jacqueline Ming Liu, Mei-Hua Tsou, Chen-Lung Huang, Ching-Ping Chen, Hsin-Sheng Wang, Chiung-Tong Chen

Journal:

Journal of Biomedical Science

Year:

2007

Language:

english

File:

PDF, 361 KB

english, 2007

22

3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes

Mohane Selvaraj Coumar, Chung-Nien Chang, Chiung-Tong Chen, Xin Chen, Chia-Hui Chien, Ting-Yueh Tsai, Jai-Hong Cheng, Hsin-Yi Wu, Chia-Hung Han, Ssu-Hui Wu, Yu-Wen Huang, Tsu Hsu, Li-Jen Hsu, Yu-Sheng

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 172 KB

english, 2007

23

Mechanisms of orexin-induced depolarizations in rat dorsal motor nucleus of vagus neurones in vitro

Ling-Ling Hwang, Chiung-Tong Chen, Nae J. Dun

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 555 KB

english, 2001

24

Immune response and pathophysiological features of Klebsiella pneumoniae liver abscesses in an animal model

Fung, Chang-Phone, Chang, Feng-Yee, Lin, Jung-Chung, Ho, Donald Ming-Tak, Chen, Chiung-Tong, Chen, Jiun-Han, Yeh, Kuo-Ming, Chen, Te-Li, Lin, Yi-Tsung, Siu, L Kristopher

Journal:

Laboratory Investigation

Year:

2011

Language:

english

File:

PDF, 774 KB

english, 2011

25

Discovery of Novel Stem Cell Mobilizers That Target the CXCR4 Receptor

Dr. Chien-Huang Wu, Dr. Chun-Ping Chang, Dr. Jen-Shin Song, Jiing-Jyh Jan, Ming-Chen Chou, Szu-Huei Wu, Kai-Chia Yeh, Dr. Ying-Chieh Wong, Chieh-Jui Hsieh, Dr. Chiung-Tong Chen, Tzu-Ting Kao, Dr. Su-Y

Journal:

Year:

2012

Language:

english

File:

PDF, 349 KB

english, 2012

26

Back Cover: Discovery of Novel Stem Cell Mobilizers That Target the CXCR4 Receptor (ChemMedChem 2/2012)

Dr. Chien-Huang Wu, Dr. Chun-Ping Chang, Dr. Jen-Shin Song, Jiing-Jyh Jan, Ming-Chen Chou, Szu-Huei Wu, Kai-Chia Yeh, Dr. Ying-Chieh Wong, Chieh-Jui Hsieh, Dr. Chiung-Tong Chen, Tzu-Ting Kao, Dr. Su-Y

Journal:

Year:

2012

File:

PDF, 940 KB

2012

27

Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins

Kiran Sonaje, Kun-Ju Lin, Michael T. Tseng, Shiaw-Pyng Wey, Fang-Yi Su, Er-Yuan Chuang, Chia-Wei Hsu, Chiung-Tong Chen, Hsing-Wen Sung

Journal:

Year:

2011

Language:

english

File:

PDF, 3.03 MB

english, 2011

28

Elucidating the signaling mechanism of an epithelial tight-junction opening induced by chitosan

Li-Wen Hsu, Pei-Ling Lee, Chiung-Tong Chen, Fwu-Long Mi, Jyuhn-Huarng Juang, Shiaw-Min Hwang, Yi-Cheng Ho, Hsing-Wen Sung

Journal:

Year:

2012

Language:

english

File:

PDF, 3.03 MB

english, 2012

29

Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells

Yun-Liang Yang, Chih-Wei Wang, Chiung-Tong Chen, Min-Hsien Wang, Chin-Fu Hsiao, Hsiu-Jung Lo

Journal:

Mycological Research

Year:

2009

Language:

english

File:

PDF, 127 KB

english, 2009

30

Central pressor effects of CART peptides in anesthetized rats

Ling-Ling Hwang, Chiung-Tong Chen, Tzu-Ling Li, Chiung-Zuan Chiu, Shih-Fang Chi

Journal:

Year:

2004

Language:

english

File:

PDF, 359 KB

english, 2004

31

Discovery of Non-Glycoside Sodium-Dependent Glucose Co-Transporter 2 (SGLT2) Inhibitors by Ligand-Based Virtual Screening

Peng, Yi-Hui, Wu, Jiun-Ming, Hsieh, Chieh-Jui, Wu, Szu-Huei, Coumar, Mohane Selvaraj, Song, Jen-Shin, Lee, Jinq-Chyi, Wu, Jian-Sung, Tsai, Chi-Hui, Chen, Chiung-Tong

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.09 MB

english, 2010

32

Quercetin and Rutin Reduced the Bioavailability of Cyclosporine from Neoral, an Immunosuppressant, through Activating P-Glycoprotein and CYP 3A4

Yu, Chung-Ping, Wu, Ping-Ping, Hou, Yu-Chi, Lin, Shiuan-Pey, Tsai, Shang-Yuan, Chen, Chiung-Tong, Chao, Pei-Dawn Lee

Journal:

Journal of Agricultural and Food Chemistry

Year:

2011

Language:

english

File:

PDF, 732 KB

english, 2011

33

Cardiovascular effects of mastoparan B and its structural requirements

Chewn-Lang Ho, Ling-Ling Hwang, Yah-Luen Lin, Chiung-Tong Chen, Hui-Ming Yu, Kung-Tsung Wang

Journal:

European Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 566 KB

english, 1994

34

Immunogenicity of mastoparan B, a cationic tetradecapeptide isolated from the hornet (Vespa basaus) venom, and its structural requirements

Ho Chewn-Lang, Lin Yah-Luen, Chen Wan-Chen, Yu Hui-Ming, Wang Kung-Tsung, Hwang Ling-Ling, Chen Chiung-Tong

Journal:

Year:

1995

Language:

english

File:

PDF, 565 KB

english, 1995

35

Diverse cellular transformation capability of overexpressed genes in human hepatocellular carcinoma

Jhy-Shrian Huang, Chuan-Chuan Chao, Teh-Li Su, Shiou-Hwei Yeh, Ding-Shinn Chen, Chiung-Tong Chen, Pei-Jer Chen, Yuh-Shan Jou

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 873 KB

english, 2004

36

3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)

John T.-A. Hsu, Teng-Kuang Yeh, Shih-Chieh Yen, Chiung-Tong Chen, Shu-Yi Hsieh, Tsu Hsu, Cheng-Tai Lu, Chun-Hwa Chen, Ling-Hui Chou, Ching-Hui Chiu, Yun-I Chang, Ya-Ju Tseng, Kuei-Rong Yen, Yu-Sheng C

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 963 KB

english, 2012

37

Anti-angiogenic action of 5,5-diphenyl-2-thiohydantoin-N10 (DPTH-N10)

Yuan Liu, Jender Wu, Pei-Yin Ho, Li-Ching Chen, Chiung-Tong Chen, Yu-Chih Liang, Cheng-Kuo Cheng, Wen-Sen Lee

Journal:

Year:

2008

Language:

english

File:

PDF, 599 KB

english, 2008

38

Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes

Hsien-Tsung Yao, PinPin Lin, Yi-Wei Chang, Chiung-Tong Chen, Meng-Tsan Chiang, Ling Chang, Yu-Chun Kuo, Hui-Ti Tsai, Teng-Kuang Yeh

Journal:

Food and Chemical Toxicology

Year:

2009

Language:

english

File:

PDF, 279 KB

english, 2009

39

Shengmai San reduces hepatic lipids and lipid peroxidation in rats fed on a high-cholesterol diet

Hsien-Tsung Yao, Yi-Wei Chang, Chiung-Tong Chen, Meng-Tsan Chiang, Ling Chang, Teng-Kuang Yeh

Journal:

Journal of Ethnopharmacology

Year:

2008

Language:

english

File:

PDF, 317 KB

english, 2008

40

The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes

Hsien-Tsung Yao, Yi-Wei Chang, Shih-Jung Lan, Chiung-Tong Chen, John T.A. Hsu, Teng-Kuang Yeh

Journal:

Year:

2006

Language:

english

File:

PDF, 542 KB

english, 2006

41

Orexins: a role in medullary sympathetic outflow

Nae J. Dun, Siok Le Dun, , Chiung-Tong Chen, Ling Ling Hwang, Ernest H. Kwok, Jaw-Kang Chang

Journal:

Regulatory Peptides

Year:

2000

Language:

english

File:

PDF, 979 KB

english, 2000

42

Differential time dependency of antiproliferative and apoptotic effects of taxol in human prostate tumors

Chiung-Tong Chen, Jessie L.-S. Au, Yuebo Gan, M. Guillaume Wientjes

Journal:

Urologic Oncology: Seminars and Original Investigations

Year:

1997

Language:

english

File:

PDF, 810 KB

english, 1997

43

H 2 O 2 Accumulation Mediates Differentiation Capacity Alteration, But Not Proliferative Decline, in Senescent Human Fetal Mesenchymal Stem Cells

Ho, Pai-Jiun, Yen, Men-Luh, Tang, Bo-Chung, Chen, Chiung-Tong, Yen, B. Linju

Journal:

Antioxidants & Redox Signaling

Year:

2013

Language:

english

File:

PDF, 762 KB

english, 2013

44

Tonic suppression of baroreceptor reflex by endogenous neurotensin in the rat

Chiung-Tong Chen, Julie Y.H. Chan, Charles D. Barnes, Samuel H.H. Chan

Journal:

Regulatory Peptides

Year:

1990

Language:

english

File:

PDF, 881 KB

english, 1990

45

Time-and concentration-dependent penetration of doxorubicin in prostate tumors

Jenny H. Zheng, Chiung-Tong Chen, Jessie L. S. Au, M. Guill Wientjes

Journal:

The AAPS Journal

Year:

2001

Language:

english

File:

PDF, 271 KB

english, 2001

46

Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors

Yao, Chun-Hsu, Song, Jen-Shin, Chen, Chiung-Tong, Yeh, Teng-Kuang, Hsieh, Tsung-Chih, Wu, Szu-Huei, Huang, Chung-Yu, Huang, Yu-Lin, Wang, Min-Hsien, Liu, Yu-Wei, Tsai, Chi-Hui, Kumar, Chidambaram Rame

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 493 KB

english, 2012

47

Structure-Based Drug Design of a Novel Family of PPARγ Partial Agonists: Virtual Screening, X-ray Crystallography, and in Vitro/in Vivo Biological Activities

Lu, I-Lin, Huang, Chien-Fu, Peng, Yi-Hui, Lin, Ying-Ting, Hsieh, Hsing-Pang, Chen, Chiung-Tong, Lien, Tzu-Wen, Lee, Hwei-Jen, Mahindroo, Neeraj, Prakash, Ekambaranellore, Yueh, Andrew, Chen, Hsin-Yi,

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 387 KB

english, 2006

48

Design and Synthesis of Tetrahydropyridothieno[2,3- d ]pyrimidine Scaffold Based Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors: The Role of Side Chain Chirality and Michael Acceptor Group for Maximal Potency

Wu, Chia-Hsien, Coumar, Mohane Selvaraj, Chu, Chang-Ying, Lin, Wen-Hsing, Chen, Yi-Rong, Chen, Chiung-Tong, Shiao, Hui-Yi, Rafi, Shaik, Wang, Sing-Yi, Hsu, Hui, Chen, Chun-Hwa, Chang, Chun-Yu, Chang,

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.54 MB

english, 2010

49

Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)

Lin, Wen-Hsing, Hsu, John T.-A., Hsieh, Shu-Yi, Chen, Chiung-Tong, Song, Jen-Shin, Yen, Shih-Chieh, Hsu, Tsu, Lu, Cheng-Tai, Chen, Chun-Hwa, Chou, Ling-Hui, Yang, Yung-Ning, Chiu, Ching-Hui, Chen, Chi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.93 MB

english, 2013

50

Preparation and Characterization of Nanoparticles Shelled with Chitosan for Oral Insulin Delivery

Lin, Yu-Hsin, Mi, Fwu-Long, Chen, Chiung-Tong, Chang, Wei-Chun, Peng, Shu-Fen, Liang, Hsiang-Fa, Sung, Hsing-Wen

Journal:

Biomacromolecules

Year:

2007

Language:

english

File:

PDF, 567 KB

english, 2007